Antiretroviral

Product Details:

• Abacavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. It is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is for adults and children who are at least 3 months old. This medicine is not a cure for HIV or AIDS.

• Before initiating Abacavir sulfate Tablets, screen for the HLA-B*5701 allele.
• Adults: 600 mg daily, administered as either 300 mg twice daily or 600 mg once daily.
• Pediatric Patients Aged 3 Months and Older: Administered either once or twice daily. Dose should be calculated on body weight (kg) and should not exceed 600 mg daily.
• Patients with Hepatic Impairment: Mild hepatic impairment - 200 mg twice daily.

Product Details:

• Prevention of CMV disease in transplant recipients
• As prophylaxis of CMV disease in subjects with AIDS
• CMV retinitis

• Oral: 1000mg TID with food.

• Oral: Following induction treatment, 1000 mg TID with food. Alternatively, 500 mg 6 times daily every 3 hours with food.

• Oral: 1000 mg TID with food.

• Oral

Product Details:

• Lamivudine is indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children.

• 150 mg orally twice a day or 300 mg orally once a day
• Use In combination with other antiretroviral agents, for the treatment of HIV-1 infection

• 100 mg orally once a day
• Duration of therapy The optimal duration of therapy is not known.
• Use For the treatment of chronic HBV infection associated with evidence of hepatitis B viral replication and active liver inflammation

• US CDC recommendations 150 mg orally twice a day or 300 mg orally once a day
• Duration of therapy 28 day

Product Details:

• HIV infection, in combination with other antiretroviral drugs. It doesn't eliminate the virus entirely, but it helps to control it.
• Chronic hepatitis B virus infection.

• Adult dosage (ages 18 years and older who weigh at least 77 lb [35 kg])
• The typical dosage is one 300-mg tablet per day.
• Child dosage (ages 12-17 years who weigh at least 77 lb [35 kg])
• The typical dosage is one 300-mg tablet per day.
• Child dosage (ages 2-11 years or weigh less than 77lb [35 kg])
• Your child's doctor will provide a dosage based on your child's specific weight.
• Child dosage (ages 0-23 months)
• Dosage for people younger than 2 years has not been established.

• Adult dosage (ages 18 years and older who weigh at least 77 lb [35 kg])
• The typical dosage is one 300-mg tablet per day.
• Child dosage (ages 12-17 years who weigh at least 77 lb [35 kg])
• The typical dosage is one 300-mg tablet per day.
• Child dosage (ages 12-17 years and weigh less than 77 lb [35 kg])
• Dosage has not been established for children who weigh less than 77 lb (35 kg).
• Child dosage (ages 0-11 years)
• Dosage for people younger than 12 years has not been established.

Product Details:

• Zidovudine is indicated in anti-retroviral combination therapy for Human Immunodeficiency Virus (HIV) infected adults and children.
• Zidovudine chemoprophylaxis is indicated for use in HIV-positive pregnant women (over 14 weeks of gestation) for prevention of maternal-foetal HIV transmission and for primary prophylaxis of HIV infection in newborn infants.

• Adults 600 mg/day in divided doses with other antiretroviral agents.
• Pediatric patients (4 weeks to <18 years of age) Dosage should be calculated based on body weight not to exceed adult dose.
• Prevention of maternal-fetal HIV-1 transmission Specific dosage instructions for mother and infant
• Patients with severe anemia and/or neutropenia Dosage interruption may be necessary.
• Renal Impairment - Recommended dosage in hemodialysis or peritoneal dialysis patients is 100 mg every 6 to 8 hours.

Product Details:

• Combination with other antiretroviral medicinal products for the treatment of HIV infected adult patients and paediatric patients (over the age of 3 months) only when other antiretrovirals can not be used.
• The duration of therapy with stavudine should be limited to the shortest time possible.

• Recommended dosage for adults
• Less than 60 kg 30 mg every 12 hours
• At least 60 kg 40 mg every 12 hours

• Newborns from birth to 13 days old 0.5 mg/kg every 12 hours
• At least 14 days old and weighing less than 30 kg 1 mg/kg every 12 hours
• Weighing at least 30 kg adult dose.
• Renal impairment Dose adjustment is recommended for CrCl ???50 mL/min.
• For oral solution Requires preparation by a pharmacist.

Product Details:

• Herpes Zoster
• Genital Herpes
• Chickenpox
• Herpes Simplex Infections
• Herpes Simplex Encephalitis

• The required dose of Aciclovir IV should be administered by slow intravenous infusion over a one-hour period.

• Adults and Adolescents (≥12 years): 5 mg/kg, 8 hourly for 7 days.
• Pediatrics (<12 years): 10 mg/kg 8 hourly for 7 days.

• Adults and Adolescents (≥12 years): 5 mg/kg 8 hourly for 5 days.

• Adults and Adolescents (≥12 years): 10 mg/kg 8 hourly for 10 days.
• Pediatrics (3 months to 12 years of age): 20 mg/kg 8 hourly for 10 days.

• 10 mg/kg 8 hourly for 10 days.

• Adults and Adolescents (≥12 years): 10 mg/kg 8 hourly for 7 days.
• Pediatrics (<12 years): 20 mg/kg 8 hourly for 7 days.
• Dose adjustment of IV for patients with acute or chronic renal impairment, based on Creatinine Clearance, Cr Cl (mL/min/1.73 m2):
• For Cr Cl = > 50 : 100% of recommended dose, 8 hourly
• For Cr Cl = 25 to 50 : 100% of recommended dose, 12 hourly
• For Cr Cl = 10 to 25 : 100% of recommended dose, 24 hourly
• For Cr Cl = 0 to 10 : 50% of recommended dose, 24 hourly

Product Details:

• Ribavirin is indicated in combination with other medicinal products for the treatment of chronic hepatitis C (CHC) in adults.
• Ribavirin is indicated in combination with other medicinal products for the treatment of chronic hepatitis C (CHC) for paediatric patients (children 3 years of age and older and adolescents) not previously treated and without liver decompensation .

• Adult PO- 400 - 600 mg two times per day. Dosage depends on the product used and patient's body weight. It is administered via inhalation in infants.

Product Details:

• Herpes Zoster
• Genital Herpes
• Chickenpox
• Herpes Simplex Infections
• Herpes Simplex Encephalitis

• The required dose of Aciclovir IV should be administered by slow intravenous infusion over a one-hour period.

• Adults and Adolescents (≥12 years): 5 mg/kg, 8 hourly for 7 days.
• Pediatrics (<12 years): 10 mg/kg 8 hourly for 7 days.

• Adults and Adolescents (≥12 years): 5 mg/kg 8 hourly for 5 days.

• Adults and Adolescents (≥12 years): 10 mg/kg 8 hourly for 10 days.
• Pediatrics (3 months to 12 years of age): 20 mg/kg 8 hourly for 10 days.

• 10 mg/kg 8 hourly for 10 days.

• Adults and Adolescents (≥12 years): 10 mg/kg 8 hourly for 7 days.
• Pediatrics (<12 years): 20 mg/kg 8 hourly for 7 days.

• For Cr Cl = > 50: 100% of recommended dose, 8 hourly
• For Cr Cl = 25 to 50: 100% of recommended dose, 12 hourly
• For Cr Cl = 10 to 25: 100% of recommended dose, 24 hourly
• For Cr Cl = 0 to 10: 50% of recommended dose, 24 hourly

Product Details:

• Lamivudine/Zidovudine is indicated in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection.

• Adults and Adolescents weighing greater than or equal to 30 kg 1 tablet orally twice daily.
• Pediatrics weighing greater than or equal to 30 kg 1 tablet orally twice daily.
• Because Lamivudine/Zidovudine is a fixed dose tablet and cannot be dose adjusted, Lamivudine/Zidovudine is not recommended in patients requiring dosage adjustment or with hepatic impairment or experiencing dose limiting adverse reactions.